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Frequently Asked Questions (DOP Testing)

Question <--- When DOP is used to test a system, does the room have to be wiped down ? --->

<---Answer--->
  

 

           No, since a comparatively small amount of DOP is released into the clean area, and most of this is swept out in th e air stream. some amy impinge on room surfaces, but his amount is negligible since the aprticles are so small they are subject to Brownian movement an remain suspended until they are finally trapped by the filter material.

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   Why should anyone use a laminar flow system ?
   What actually a laminar air flow system ?
   How are the High-efficiency particulate air ( HEPA filters) tested ?
   what specifications or standards apply to testing the filters in place ?
   Is this in-place filter test the same one as the filter manufacturer uses ?
   What is the procedure for in-place test?
   What does percent of penetration mean ?
   Why was 0.01% established as a significant ?
   Why can't the leak test be run with ambient air within a room ?
   If plates to obtain bacterial counts are used, must the in-place test still be run ?
   Can leaks not be detected by agar plates ?
   How about impingement devices ? 
   Is DOP aerosol harmful to the filters ?
   What happens to the DOP once it is in the system ?
   When DOP is used to test a system, does the room have to be wiped down ?
   Has DOP test been accepted by the pharmaceutical industry ?
   with reference to Fed. Std. 209b, What is the relationship of the various classes of       clean rooms( 100, 10 000, and 100 000 ) to the 0.01% figure ?
   Can a particle counter not be used to determine the class of the room ?
   But isn't a particle count important data ?
   But, why can't leak test be carried out with a particle counters ?
   What are the advantages of the DOP in-place test over attempting a leak test       with a particle counter ?
   How often should the DOP in-place test to be run ?
   What qualifications are necessary for in-place test personnel ?
   when should the HEPA filters be replaced ?
   Do all filter material makers and filter manufacturers use the same mehtods for      testing their products ?